Slow and fast transient potassium currents in cultured rat hippocampal cells.
نویسندگان
چکیده
منابع مشابه
Two pharmacologically and kinetically distinct transient potassium currents in cultured embryonic mouse hippocampal neurons.
Transient potassium currents in mammalian central neurons influence both the repolarization of single action potentials and the timing of repetitive action potential generation. How these currents are integrated into neuronal function will depend on their specific properties: channel availability at the resting potential, activation threshold, inactivation rate, and current density. We here rep...
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............................................................................................ ii ACKNOWLEDGEMENTS .............................................................................. iii DEDICATION ........................................................................................... iv TABLE OF CONTENTS ................................................................................
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The kinetics of potassium tail currents have been studied in the omohyoid muscle of the rat using the three-microelectrode voltage-clamp technique. The currents were elicited by a two-pulse protocol in which a conditioning pulse to open channels was followed by a test step to varying levels. The tail currents reversed at a single well-defined potential (VK). At hyperpolarized test potentials (-...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1992
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1992.sp018932